RNA SECONDARY STRUCTURE PREDICTION, A CUCKOO SEARCH APPROACH

Amandeep Sharma, Amanpal Singh

Abstract: RNA secondary structure prediction uses techniques like crystallography, NMR spectroscopy etc. Computation based techniques estimate the possible base pairs that could be formed in RNA. Soft computing techniques generally select some random pair or pair sequences and then check them according to some parameters. The final sequence of RNA which is closest to the required fitness is selected as the final structure. The cuckoo search approach is good for finding the feasible search space locations. Cuckoo search approach feasibly provides results for the detection of base pairs in the RNA and the RNA secondary structure

Keywords: DNA, RNA, base pairs, pseudo-knots, structure, soft computing, techniques.

DOI: https://doi.org/10.15623/ijret.2015.0412029