IN VITRO ANTIOXIDANT ACTIVITIES OF SALAZINIC ACID AND ITS DERIVATIVE HEXAACETYL SALAZINIC ACID

G. Selvaraj, A. Tinabaye, R. Ananthi

Abstract: The stress generated upon oxidation can lead to the production of free radicals which may cause many degenerative diseases. In order to eliminate the free radicals antioxidants have been used. The present study was to estimate the antioxidant activity of salazinic acid and its derivative hexaacetyl salazinic acid. The antioxidant property were studied under the categories DPPH, FRAP, Metal chelating activity, Hydroxyl scavenging activity, Lipid peroxidation activity, Phosphomolybdenum activity, Superoxide dismutase activity. We have isolated salazinic acid from the lichen Parmotrema reticulatum collected from Kodaikanal hills. The Derivative hexaacetyl salazinic acid was also prepared. Both the compounds were subjected to determine the in vitro antioxidant activity and their IC50 value are also calculated. The Lichen metabolite and its derivative have shown better antioxidant efficiency.

Keywords: Oxidative stress, Salazinic acid, Hexaacetyl salazinic acid, Tannic acid.

DOI: https://doi.org/10.15623/ijret.2015.0402046