MICROWAVE ASSISTED ECO FRIENDLY SYNTHESIS OF 2H-PYRIDO [1, 2-A] PYRIMIDINE-2-ONE

Sharulatha V, Indumathi U, Priyadharshini S

Abstract: Pyrido primidines are important class of heterocylic compounds because of their use in medicinal and agro chemistry as scaffolds for active agents such as antiviral, antiulcer, antimalarial, antifungal and herbicidal agents. Herein we report the synthesis of 2Hpyrido[1,2-a]pyrimidine-2-ones by the reaction of itaconic acid with 2-amino pyridine in tow steps under classical and microwave technology.

Keywords: microwave synthesis 2H-pyrido [1, 2-a] pyrimidine-2-one

DOI: https://doi.org/10.15623/ijret.2014.0308001